PharmGKB: the Pharmacogenetics Knowledge Base
نویسندگان
چکیده
منابع مشابه
PharmGKB: the Pharmacogenetics Knowledge Base
The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under ...
متن کاملThe pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge
PharmGKB is a knowledge base that captures the relationships between drugs, diseases/phenotypes and genes involved in pharmacokinetics (PK) and pharmacodynamics (PD). This information includes literature annotations, primary data sets, PK and PD pathways, and expert-generated summaries of PK/PD relationships between drugs, diseases/phenotypes and genes. PharmGKB's website is designed to effecti...
متن کاملOntology Development for a Pharmacogenetics Knowledge Base
Research directed toward discovering how genetic factors influence a patient's response to drugs requires coordination of data produced from laboratory experiments, computational methods, and clinical studies. A public repository of pharmacogenetic data should accelerate progress in the field of pharmacogenetics by organizing and disseminating public datasets. We are developing a pharmacogeneti...
متن کاملPharmGKB: A Resource to Link Genotype and Phenotype in Pharmacogenetics
The PharmGKB (http://www.pharmgkb.org/) is a pharmacogenetics and pharmacogenomics knowledge base built to support the representation, storage, analysis and dissemination of genotype and phenotype data. We have collected genetic sequence data from research centers in which polymorphic variations in genes of pharmacogenetic interest have been characterized in particular populations. PharmGKB als...
متن کاملPharmacogenetics research network and knowledge base: 1st annual scientific meeting.
The National Institute of General Medical Sciences of the National Institutes of Health recently established a collaborative group of scientists, called the Pharmacogenetics Research Network. Central to the network is a shared, state-of-the-art data repository, the Pharmacogenetics Knowledge Base (PharmGKB), which is housed at Stanford University. Network investigators deposit pharmacogenetic d...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2002
ISSN: 1362-4962
DOI: 10.1093/nar/30.1.163